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Article

Early emergence of ganciclovir-resistant human cytomegalovirus strains in children with primary combined immunodeficiency.

The Journal of infectious diseases - 1 Aug 1998

Wolf D G, Yaniv I, Honigman A, Kassis I, Schonfeld T, Ashkenazi S

Abstract excerpt

Children with primary combined immunodeficiency (CID) and human cytomegalovirus (HCMV) infection often deteriorate despite antiviral therapy. In this study, the emergence of ganciclovir-resistant strains was examined in 6 children with CID and HCMV infection, using sequence analysis of the HCMV UL97 gene and virus susceptibility assays. Mutations in the proposed ATP binding site associated with ganciclovir...

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Identifiers

PMID: 9697738
DOI: 10.1086/517468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Early emergence of ganciclovir-resistant human cytomegalovirus strains in children with primary combined immunodeficiency.PMID 9697738Read ↗

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Rapid Detection Directly from Patient Serum Samples of Human Cytomegalovirus UL97 Mutations Conferring Ganciclovir ResistanceSemantic proximity Read ↗

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