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Article

Association of intergenic polymorphism of organic anion transporter 1 and 3 genes with hypertension and blood pressure response to hydrochlorothiazide.

American journal of hypertension - 1 Mar 2011

Han Yun-Feng, Fan Xiao-Han, Wang Xiao-Jian, Sun Kai, Xue Hao, Li Wei-Ju, Wang Yi-Bo, Chen Jing-Zhou, Zhen Yi-Song, Zhang Wei-Li, Zhou Xianliang, Hui Rutai

Abstract excerpt

BACKGROUND: Organic anion transporter (OAT) 1 and OAT3, encoded by a tightly linked gene pair, play a key role in renal secretion of diuretics. However, no study has yet examined the influence of OAT1 and OAT3 polymorphisms on high blood pressure (BP) and the response to thiazide diuretics. We hypothesized that intergenic polymorphisms between OAT1 and OAT3 might be associated with adult hypertension and the...

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Identifiers

PMID: 21164499
DOI: 10.1038/ajh.2010.191

Genes

OAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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