Article
Genotypic diversity of complement component C4 does not predict kidney transplant outcome.
Journal of the American Society of Nephrology : JASN - 1 Feb 2011
Wahrmann Markus, Döhler Bernd, Ruhenstroth Andrea, Haslacher Helmuth, Perkmann Thomas, Exner Markus, Rees Andrew J, Böhmig Georg A
Abstract excerpt
Gene copy number of complement component C4, which varies among individuals, may determine the intrinsic strength of the classical complement pathway. Presuming a major role of complement as an effector in transplant rejection, we hypothesized that C4 genetic diversity may partially explain the v...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
