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Article

Genotypic diversity of complement component C4 does not predict kidney transplant outcome.

Journal of the American Society of Nephrology : JASN - 1 Feb 2011

Wahrmann Markus, Döhler Bernd, Ruhenstroth Andrea, Haslacher Helmuth, Perkmann Thomas, Exner Markus, Rees Andrew J, Böhmig Georg A

Abstract excerpt

Gene copy number of complement component C4, which varies among individuals, may determine the intrinsic strength of the classical complement pathway. Presuming a major role of complement as an effector in transplant rejection, we hypothesized that C4 genetic diversity may partially explain the variation in allograft outcomes. This retrospective study included 1969 deceased-donor kidney transplants randomly...

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Identifiers

PMID: 21164027
DOI: 10.1681/ASN.2010050513
PMCID: PMC3029909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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