Article
Renin gene haplotype diversity and linkage disequilibrium in two Mexican and one German population samples.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2011
Valdez-Velazquez Laura L, Mendoza-Carrera Francisco, Perez-Parra Sandra A, Rodarte-Hurtado Katia, Sandoval-Ramirez Lucila, Montoya-Fuentes Héctor, Quintero-Ramos Antonio, Delgado-Enciso Ivan, Montes-Galindo Daniel A, Gomez-Sandoval Zeferino, Olivares Norma, Rivas Fernando
Abstract excerpt
INTRODUCTION: Renin is the main rate-limiting enzyme in the renin-angiotensin-aldosterone system. Its gene, REN, is a candidate crucial factor in essential hypertension and cardiovascular disease. The aim of this study was to evaluate allele and haplotype distributions of REN polymorphisms, and t...
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