Article
Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Nov 1999
Frossard P M, Kane J P, Malloy M J, Bener A
Abstract excerpt
As renin is the key enzyme of the renin-angiotensin-aldosterone system, the renin gene (REN) represents a good candidate quantitative trait locus for investigations aimed at uncovering the molecular and genetic influences implicated in the molecular etiology of essential hypertension. Among the various polymorphic markers that are available at the REN gene locus, an MboI dimorphic site located in the ninth intron...
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