Article
Haplotypes of the human renin gene associated with essential hypertension and stroke.
Journal of human hypertension - 1 Jan 2001
Frossard P M, Malloy M J, Lestringant G G, Kane J P
Abstract excerpt
The human renin gene (REN) is a good candidate in studies aimed at unravelling the genetic basis of essential hypertension and stroke. We previously established that both a BglI and an MboI dimorphisms (located respectively in the first and ninth introns of the REN gene) were associated with essential hypertension in a population of hyperlipidaemic US subjects. In this association (retrospective case-control)...
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