Article
Human renin gene BglI dimorphism associated with hypertension in two independent populations.
Clinical genetics - 1 Dec 1999
Frossard P M, Lestringant G G, Malloy M J, Kane J P
Abstract excerpt
The renin (REN) gene is a good candidate that could underlie an individual's genetic susceptibility to human essential hypertension (EHT). We describe here a polymerase chain reaction-based assay for detection of a BglI dimorphic site located in the first intron of the REN gene. In this retrospective, case-control, association study, we investigated BglI allele and genotype distributions in 554 subjects (280...
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