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Article

Molecular and idiotypic analysis of antibodies to Cryptococcus neoformans glucuronoxylomannan

1 Sept 1994

Abstract excerpt

Antibodies to the Cryptococcus neoformans capsular glucuronoxylomannan (GXM) form the basis of two potential therapeutic intervention strategies, i.e., conjugate vaccines and passive antibody therapy. To better understand the molecular basis of the antibody response, the heavy- and light-chain immunoglobulin variable region (VH and VL, respectively) sequences of seven monoclonal antibodies (MAbs) to GXM were...

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Identifiers

PMID: 8063403
DOI: 10.1128/iai.62.9.3864-3872.1994

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