Article
Sequence diversity in the A domain of Staphylococcus aureus fibronectin-binding protein A.
BMC microbiology - 8 May 2008
Loughman Anthony, Sweeney Tara, Keane Fiona M, Pietrocola Giampiero, Speziale Pietro, Foster Timothy J
Abstract excerpt
BACKGROUND: Fibronectin-binding protein A (FnBPA) mediates adhesion of Staphylococcus aureus to fibronectin, fibrinogen and elastin. We previously reported that S. aureus strain P1 encodes an FnBPA protein where the fibrinogen/elastin-binding domain (A domain) is substantially divergent in amino acid sequence from the archetypal FnBPA of S. aureus NCTC8325, and that these variations created differences in...
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