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Article

Modeling the effect of susceptibility factors (HLA and PTPN22) in rheumatoid arthritis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Perdry Hervé, Clerget-Darpoux Françoise

Abstract excerpt

Numerous genome-wide analyses on common multifactorial diseases have been recently published in providing, for each associated Single Nucleotide Polymorphism (SNP), an Odds Ratio (OR), either for one of the susceptibility variant allele versus none, or for two copies of it versus one copy. Besides the poor information attached to these measures, it is a simplistic idea to reduce the effect of a gene to the one of...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to HLA-DR Antigens

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Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Identifiers

PMID: 21153621
DOI: 10.1007/978-1-60327-416-6_15

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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