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Article

rs2476601 in PTPN22 gene in rheumatoid arthritis and periodontitis-a possible interface?

Journal of translational medicine - 15 Oct 2020

Schulz Susanne, Zimmer Pauline, Pütz Natalie, Jurianz Elisa, Schaller Hans-Günter, Reichert Stefan

Abstract excerpt

BACKGROUND: Rheumatoid arthritis (RA) and periodontitis (PD) are proven to share common risk markers, including genetic factors. In the present study we focused on genetic variants in PTPN22 (rs2476601), PADI4 (rs2240340), CTLA4 genes (rs3087243) and its impact on RA and PD. MATERIALS AND METHODS: In the study 111 RA patients and 256 systemically healthy controls were involved. A subdivision of patients and...

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Share to Genetic Predisposition to Disease
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Share to Polymorphism, Single Nucleotide
Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Identifiers

PMID: 33059697
DOI: 10.1186/s12967-020-02548-w
PMCID: PMC7559817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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