Article
Association of polymorphic variants of PTPN22, TNF and VDR genes in children with lupus nephritis: A study in Colombian family triads.
Biomedica : revista del Instituto Nacional de Salud - 1 Jun 2017
Garavito Gloria, Egea Eduardo, Fang Luis, Malagón Clara, Olmos Carlos, González Luz, Guarnizo Pilar, Aroca Gustavo, López Guillermo, Iglesias Antonio
Abstract excerpt
INTRODUCTION: Systemic lupus erythematosus is an autoimmune disease in which the severity varies according to race, sex and age of onset. This variation is also observed in the genetic markers associated with the disease, including PTPN22, VDR and TNF genes. The genetic stratification in different populations worldwide can influence the variability. OBJECTIVE: To analyze the heritability of PTPN22, VDR and TNF...
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