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Article

Sex differential genetic effect of chromosome 9p21 on subclinical atherosclerosis.

PloS one - 30 Nov 2010

Lin Hsiu-Fen, Tsai Pei-Chien, Lin Ruey-Tay, Khor Gim-Thean, Sheu Sheng-Hsiung, Juo Suh-Hang Hank

Abstract excerpt

BACKGROUND: Chromosome 9p21 has recently been shown to be a risk region for a broad range of vascular diseases. Since carotid intima-media thickness (IMT) and plaque are independent predictors for vascular diseases, the association between 9p21 and these two phenotypes was investigated. METHODOLOGY/PRINCIPAL FINDINGS: Carotid segment-specific IMT and plaques were obtained in 1083 stroke- and myocardial...

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Identifiers

PMID: 21152093
DOI: 10.1371/journal.pone.0015124
PMCID: PMC2994883

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