Article
Single polymorphism nucleotide rs1333049 on chromosome 9p21 is associated with carotid plaques but not with common carotid intima-media thickness in older adults. A combined analysis of the Three-City and the EVA studies.
Atherosclerosis - 1 May 2012
Plichart Matthieu, Empana Jean-Philippe, Lambert Jean-Charles, Amouyel Philippe, Tiret Laurence, Letenneur Luc, Berr Claudine, Tzourio Christophe, Ducimetière Pierre
Abstract excerpt
OBJECTIVES: To address the relationship of rs1333049, the 9p21 variant showing the strongest association with coronary heart disease (CHD), with carotid plaques and plaque-free common carotid artery intima-media thickness (CCA-IMT) in older adults from 2 French population-based cohorts. METHODS: We genotyped for rs1333049, 4097 CHD-free participants including 3191 aged 65-86 years from the Three-City (3C) Study...
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