Article
9p21 is a shared susceptibility locus strongly for coronary artery disease and weakly for ischemic stroke in Chinese Han population.
Circulation. Cardiovascular genetics - 1 Aug 2009
Ding Hu, Xu Yujun, Wang Xiaojing, Wang Qi, Zhang Lan, Tu Yuanchao, Yan Jiangtao, Wang Wei, Hui Rutai, Wang Cong-Yi, Wang Dao Wen
Abstract excerpt
BACKGROUND: Recent studies on genome-wide association have identified common variants on chromosome 9p21 associated with coronary artery disease (CAD). Given that ischemic stroke and CAD share several aspects of etiology and pathogenesis, we investigated the association of variants on chromosome 9p21 with ischemic stroke and CAD in the Chinese Han population by capturing the majority of diversity in this locus...
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