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Article

Genetic mechanisms mediating atherosclerosis susceptibility at the chromosome 9p21 locus.

Current atherosclerosis reports - 1 Jun 2011

Cunnington Michael S, Keavney Bernard

Abstract excerpt

Recent genome-wide association studies have demonstrated that common genetic variants in a region of chromosome 9p21 confer risk of coronary artery disease (CAD) and other atherosclerotic conditions. Although the absolute increase in risk is small (some 20-30% increase in risk of CAD per copy of the deleterious alleles), the common occurrence of the variants means that their effect on the population risk of...

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Identifiers

PMID: 21487702
DOI: 10.1007/s11883-011-0178-z

Genes

CAD

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