Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of CDKN2A mutations in pancreatic cancer patients: implications for genetic counseling.

European journal of human genetics : EJHG - 1 Apr 2011

McWilliams Robert R, Wieben Eric D, Rabe Kari G, Pedersen Katrina S, Wu Yanhong, Sicotte Hugues, Petersen Gloria M

Abstract excerpt

Germline mutations in CDKN2A have been reported in pancreatic cancer families, but genetic counseling for pancreatic cancer risk has been limited by lack of information on CDKN2A mutation carriers outside of selected pancreatic or melanoma kindreds. Lymphocyte DNA from consecutive, unselected white non-Hispanic patients with pancreatic adenocarcinoma was used to sequence CDKN2A. Frequencies of mutations that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinase Inhibitor p16
Share to Genetic Counseling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Melanoma

Share to Pancreatic Neoplasms

Share to Penetrance

Share to Skin Neoplasms

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 21150883
DOI: 10.1038/ejhg.2010.198
PMCID: PMC3060321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of CDKN2A mutations in pancreatic cancer patients: implications for genetic counseling.PMID 21150883Read ↗

Familial melanoma, pancreatic cancer and germline CDKN2A mutationsSemantic proximity Read ↗

Genotype-phenotype correlations for pancreatic cancer risk in Dutch melanoma families with pathogenic CDKN2A variants.Semantic proximity Read ↗

The Role of Inherited Pathogenic CDKN2A Variants in Susceptibility to Pancreatic Cancer.Semantic proximity Read ↗

CDKN2A Gene Mutations: Implications for Hereditary Cancer SyndromesSemantic proximity Read ↗

Prospective study of germline genetic testing in incident cases of pancreatic adenocarcinoma.Semantic proximity Read ↗

CDKN2A germline mutations in familial pancreatic cancer.Semantic proximity Read ↗

Association between breast cancer, pancreatic cancer, and melanoma in a CDKN2A variant common in the Hispanic population.Semantic proximity Read ↗

Multiple rare variants in high-risk pancreatic cancer-related genes may increase risk for pancreatic cancer in a subset of patients with and without germline CDKN2A mutations.Semantic proximity Read ↗

Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families.Semantic proximity Read ↗

CDKN2AGermline Rare Coding Variants and Risk of Pancreatic Cancer in Minority PopulationsSemantic proximity Read ↗

Pancreatic Ductal Carcinoma Risk Associated With Hereditary Cancer-Risk Genes.Semantic proximity Read ↗

Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.