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Article

CDKN2A germline mutations in familial pancreatic cancer.

Annals of surgery - 1 Dec 2002

Bartsch Detlef K, Sina-Frey Mercedes, Lang Sven, Wild Anja, Gerdes Berthold, Barth Peter, Kress Ralf, Grützmann Robert, Colombo-Benkmann Mario, Ziegler Andreas, Hahn Stephan A, Rothmund Matthias, Rieder Harald

Abstract excerpt

OBJECTIVE: To evaluate the prevalence of mutations in the CDKN2A gene encoding p16 and p14 in familial pancreatic cancer (FPC). SUMMARY BACKGROUND DATA: The genetic basis of FPC is still widely unknown. Recently, it has been shown that germline mutations in the p16 tumor suppressor gene can predispose to pancreatic cancer. The presence of p14 germline mutations has yet not been determined in this setting....

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Identifiers

PMID: 12454511
DOI: 10.1097/00000658-200212000-00005
PMCID: PMC1422639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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