Article
Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families.
Familial cancer - 1 Sept 2010
Slater Emily P, Langer Peter, Fendrich Volker, Habbe Nils, Chaloupka Brunhilde, Matthäi Elvira, Sina Mercedes, Hahn Stephan A, Bartsch Detlef K
Abstract excerpt
Previous small scale studies reported that deleterious BRCA2 and CDKN2a germline mutations contribute to a subset of families with inherited pancreatic cancer. As the prevalence of those mutations in the setting of familial pancreatic cancer is still not well defined for the German population, we evaluated the presence of BRCA2 and CDKN2a germline mutations in a large cohort of familial pancreatic cancer (FPC)...
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