Article
Mechanisms of nitric oxide-mediated inhibition of EMT in cancer: inhibition of the metastasis-inducer Snail and induction of the metastasis-suppressor RKIP.
Cell cycle (Georgetown, Tex.) - 15 Dec 2010
Baritaki Stavroula, Huerta-Yepez Sara, Sahakyan Anna, Karagiannides Iordanis, Bakirtzi Kyriaki, Jazirehi Ali, Bonavida Benjamin
Abstract excerpt
The role of nitric oxide (NO) in cancer has been controversial and is based on the levels of NO and the responsiveness of the tumor type. It remains unclear whether NO can inhibit the epithelial to mesenchymal transition (EMT) in cancer cells. EMT induction is mediated, in part, by the constituti...
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