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DNA methylation markers for kidney function and progression of diabetic kidney disease

15 May 2023

Abstract excerpt

Epigenetic markers are potential biomarkers for diabetes and related complications. Using a prospective cohort from the Hong Kong Diabetes Register, we perform two independent epigenome-wide association studies to identify methylation markers associated with baseline estimated glomerular filtration rate (eGFR) and subsequent decline in kidney function (eGFR slope), respectively, in 1,271 type 2 diabetes subjects....

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PMID: 37188670
DOI: 10.1038/s41467-023-37837-7

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