Article
Multiple mucin genes polymorphisms are associated with gallstone disease in Chinese men.
Clinica chimica acta; international journal of clinical chemistry - 18 Mar 2011
Chuang Shih-Chang, Juo Suh-Hang Hank, Hsi Edward, Wang Shen-Nien, Tsai Pei-Chien, Yu Ming-Lung, Lee King-Teh
Abstract excerpt
BACKGROUND: Gallstone is a complex disease caused by multiple environmental and genetic factors. One of these is mucin glycoproteins. This case-control study aimed to investigate the association between single nucleotide polymorphisms (SNPs) at the MUC1-4 genes and gallstone. METHODS: The study included 475 cases and 941 controls. Eight tagging SNPs were selected: one at MUC1, two at MUC2, and five at MUC4. There...
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