Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endogenous retroviral long terminal repeats within the HLA-DQ locus.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990

Kambhu S, Falldorf P, Lee J S

Abstract excerpt

Two endogenous retroviral long terminal repeats (LTRs) were found in the human major histocompatibility complex locus HLA-DQ. The solo LTRs, unlinked to retrovirus structural genes, are located approximately 5 kilobases apart from each other and in the same transcriptional orientation, which is opposite to that for the HLA-DQB1 gene. These elements exhibit greater than 90% homology to the LTRs of the human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 2114643
DOI: 10.1073/pnas.87.13.4927
PMCID: PMC54234

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Endogenous retroviral long terminal repeats within the HLA-DQ locus.PMID 2114643Read ↗

An endogenous retroviral long terminal repeat at the HLA-DQB1 gene locus confers susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

Human endogenous retrovirus (HERVK9) structural polymorphism with haplotypic HLA-A allelic associations.Semantic proximity Read ↗

Distribution of HERV-LTR elements in the 5'-flanking region of HLA-DQB1 and association with autoimmunity.Semantic proximity Read ↗

Preliminary evidence that an endogenous retroviral long-terminal repeat (LTR13) at the HLA-DQB1 gene locus confers susceptibility to Addison's disease.Semantic proximity Read ↗

The presence or absence of a retroviral long terminal repeat influences the genetic risk for type 1 diabetes conferred by human leukocyte antigen DQ haplotypes. Belgian Diabetes Registry.Semantic proximity Read ↗

Impact of endogenous intronic retroviruses on major histocompatibility complex class II diversity and stability.Semantic proximity Read ↗

HLA DQA1 genes generate multiple transcripts by alternative splicing and polyadenylation of the 3' untranslated region.Semantic proximity Read ↗

Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes.Semantic proximity Read ↗

Structure and evolution of the promoter regions of the DQA genes.Semantic proximity Read ↗

A retroviral long terminal repeat adjacent to the HLA DQB1 gene (DQ-LTR13) modifies Type I diabetes susceptibility on high risk DQ haplotypes.Semantic proximity Read ↗

5' regulatory nucleotide sequence of an HLA-A*0101null allele.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.