Endogenous retroviral long terminal repeats within the HLA-DQ locus.

doi:10.1073/pnas.87.13.4927

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Article

Endogenous retroviral long terminal repeats within the HLA-DQ locus.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990

Kambhu S, Falldorf P, Lee J S

Abstract excerpt

Two endogenous retroviral long terminal repeats (LTRs) were found in the human major histocompatibility complex locus HLA-DQ. The solo LTRs, unlinked to retrovirus structural genes, are located approximately 5 kilobases apart from each other and in the same transcriptional orientation, which is opposite to that for the HLA-DQB1 gene. These elements exhibit greater than 90% homology to the LTRs of the human...

Topics

B-Lymphocytes
Base Sequence
Cell Line
Cloning, Molecular
Cosmids
Genes, MHC Class II
Genetic Variation
HLA-DQ Antigens
Homozygote
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligonucleotide Probes

Polymerase Chain Reaction

Polymorphism, Genetic

Repetitive Sequences, Nucleic Acid

Restriction Mapping

Retroviridae

Sequence Homology, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 2114643
DOI: 10.1073/pnas.87.13.4927
PMCID: PMC54234

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2114643-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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