Article
Impact of endogenous intronic retroviruses on major histocompatibility complex class II diversity and stability.
Journal of virology - 1 Jul 2008
Doxiadis Gaby G M, de Groot Nanine, Bontrop Ronald E
Abstract excerpt
The major histocompatibility complex (MHC) represents a multigene family that is known to display allelic and gene copy number variations. Primate species such as humans, chimpanzees (Pan troglodytes), and rhesus macaques (Macaca mulatta) show DRB region configuration polymorphism at the population level, meaning that the number and content of DRB loci may vary per haplotype. Introns of primate DRB alleles differ...
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