Article
Distribution of HERV-LTR elements in the 5'-flanking region of HLA-DQB1 and association with autoimmunity.
Immunogenetics - 1 Mar 2001
Pascual M, Martin J, Nieto A, Giphart M J, van der Slik A R, de Vries R R, Zanelli E
Abstract excerpt
We established the detailed polymorphism of the 5'-flanking region and the first exon of the human leukocyte antigen (HLA)-DQB1 alleles. One hundred and forty-five Spanish rheumatoid arthritis (RA) patients and 200 healthy voluntary blood donors from southern Spain along with 42 B-cell lines were analyzed for the presence of the retrovirus-derived long terminal repeats (LTRs) LTR3, LTR5, and LTR13. LTR3...
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