Article
Overexpression of PaParp encoding the poly(ADP-ribose) polymerase of Podospora anserina affects organismal aging.
Mechanisms of ageing and development - 1 Jan 2000
Müller-Ohldach Mathis, Brust Diana, Hamann Andrea, Osiewacz Heinz D
Abstract excerpt
Poly(ADP-ribose) polymerases (PARPs) are a diverse group of proteins present in all multicellular eukaryotes. They catalyze the NAD(+)-dependent modification of proteins with poly(ADP-ribose). Poly(ADP-ribosyl)ation plays a key role in a plethora of processes including DNA repair, tumor progressi...
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