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Article

A novel BDNF polymorphism affects plasma protein levels in interaction with early adversity in rhesus macaques.

Psychoneuroendocrinology - 1 Apr 2011

Cirulli Francesca, Reif Andreas, Herterich Sabine, Lesch K Peter, Berry Alessandra, Francia Nadia, Aloe Luigi, Barr Christina S, Suomi Stephen J, Alleva Enrico

Abstract excerpt

Early stressful events can increase vulnerability for psychopathology, although knowledge on the effectors is still limited. In this report we describe the characterization of a single nucleotide polymorphism (SNP) in rhesus macaques, which results in a Val to Met transition in the pro-BDNF domain, similar to a well described variant in the human gene. Further, we tested the hypothesis that peripheral levels of...

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Identifiers

PMID: 21145664
DOI: 10.1016/j.psyneuen.2010.10.019
PMCID: PMC3046296

Genes

BDNF
SPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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