Article
Associations between parenting behavior and anxiety in a rodent model and a clinical sample: relationship to peripheral BDNF levels.
Translational psychiatry - 20 Nov 2012
Dalle Molle R, Portella A K, Goldani M Z, Kapczinski F P, Leistner-Segal S, Leistner-Segala S, Salum G A, Manfro G G, Silveira P P
Abstract excerpt
Adverse early-life environment is associated with anxiety-like behaviors and disorders. Brain-derived neurotrophic factor (BDNF) is sensitive to this environment and could be a marker of underlying brain changes. We aimed at evaluating the development of anxiety-like behaviors in a rat model of early adversity, as well as the possible association with BDNF levels. Similar associations were investigated in a...
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