Article
Association between the recombinant human serotonin transporter linked promoter region polymorphism and behavior in rhesus macaques during a separation paradigm.
Development and psychopathology - 1 Jan 2007
Spinelli Simona, Schwandt Melanie L, Lindell Stephen G, Newman Timothy K, Heilig Markus, Suomi Stephen J, Higley J Dee, Goldman David, Barr Christina S
Abstract excerpt
Human studies have suggested an association between a variable length polymorphism in the serotonin transporter gene promoter region and vulnerability to anxiety and depression. Relative to the long (l) allele, the short (s) allele increases the risk of developing depression in individuals exposed to stressful life events. An orthologue of the human variant is present in rhesus macaques and allows for studies in...
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