Article
IgM monoclonal gammopathy/Waldenström's macroglobulinemia: a morphological and immunophenotypic study of the bone marrow.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 1990
Feiner H D, Rizk C C, Finfer M D, Bannan M, Gottesman S R, Chuba J V, Amorosi E
Abstract excerpt
The presence of a monoclonal paraprotein in the serum or urine raises the possibility of myeloma or lymphoma/leukemia. Yet, in a significant proportion of individuals with serum paraproteins, particularly those with low levels of paraprotein, clinical and routine bone marrow evaluation is not diagnostic of an underlying neoplasm. The purpose of this study was to define the pathologic basis for macroglobulinemia...
Topics
- Aged
- Aged, 80 and over
- Bone Marrow
- Female
- Flow Cytometry
- Humans
- Immunoelectrophoresis
- Immunoenzyme Techniques
- Immunoglobulin M
- Male
- Microscopy, Fluorescence
