Article
Immunophenotypic analysis of Waldenstrom's macroglobulinemia.
Seminars in oncology - 1 Apr 2003
San Miguel J F, Vidriales M B, Ocio E, Mateo G, Sánchez-Guijo F, Sánchez M L, Escribano L, Bárez A, Moro M J, Hernández J, Aguilera C, Cuello R, García-Frade J, López R, Portero J, Orfao A
Abstract excerpt
Immunophenotyping has become an essential tool for diagnosis of hematological malignancies. By contrast, for diagnosis of Waldenstrom's macroglobulinemia (WM) immunophenotyping is used only occasionally. From 150 patients with a IgM monoclonal gammopathy we have selected 60 cases with (1) morphological lymphoplasmocytoid bone marrow (BM) infiltration (>20%); (2) IgM paraprotein (>10g/L); and (3) absence of...
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