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Article

Immunocytochemical detection of kappa and lambda light chain V region subgroups in human B-cell malignancies.

The American journal of pathology - 1 Oct 1990

Solomon A, Weiss D T, Macy S D, Antonucci R A

Abstract excerpt

We have used a sensitive immunoperoxidase method and highly specific anti-light chain antisera to determine the light chain variable region (VL) subgroup nature of cytoplasmic (c) and cell surface (s) Ig expressed by human monoclonal plasma cells and B lymphocytes. The immunocytochemical characte...

Topics

Amyloidosis
Antibody Specificity
Binding Sites
Bone Marrow
Humans
Immune Sera
Immunoenzyme Techniques
Immunoglobulin kappa-Chains
Immunoglobulin lambda-Chains
Leukemia, B-Cell
Leukemia, Lymphocytic, Chronic, B-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymph Nodes

Lymphoma, B-Cell

Multiple Myeloma

Phenotype

Waldenstrom Macroglobulinemia

Source

Open in PubMed Open full text

Identifiers

PMID: 2121042
PMCID: PMC1877536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2121042-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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