Article
Combined utility of gene rearrangement analysis and flow cytometry in the diagnosis of lymphoproliferative disease in the bone marrow.
Hematologic pathology - 1 Jan 1990
Sandhaus L M, Voelkerding K V, Dougherty J, Raska K
Abstract excerpt
The diagnosis of lymphoma involving bone marrow is often complicated by the presence of nonspecific lymphoid aggregates. Morphologic criteria may not permit the distinction of benign from malignant lymphoid aggregates with certainty in all cases. We combined morphology with immunophenotypic and immunogenotypic analyses of aspirated marrow cells to develop more reliable criteria for the diagnosis of marrow...
Topics
- Aged
- Biopsy, Needle
- Bone Marrow Diseases
- Female
- Flow Cytometry
- Gene Rearrangement
- Genotype
- Humans
- Immunoenzyme Techniques
- Immunophenotyping
- Lymphoma, Non-Hodgkin