Article
CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans.
The pharmacogenomics journal - 1 Apr 2012
Llerena A, Dorado P, Ramírez R, González I, Alvarez M, Peñas-Lledó E M, Pérez B, Calzadilla L R
Abstract excerpt
CYP2D6 genotype and debrisoquine metabolic ratio (MR) were analyzed in 133 Nicaraguan Mestizos (NMs) and 260 Cubans divided into Cuban Mestizos (CMs) and White Cubans (WCs). The frequencies of poor metabolizers (MR12.6) were 6% in NMs, 3.9% in CMs and 5.3% in WCs. The frequencies of ultrarapid m...
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