Article
Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster.
Molecular and cellular biology - 1 Feb 2011
Li Hua-Bing, Müller Martin, Bahechar Ilham Anne, Kyrchanova Olga, Ohno Katsuhito, Georgiev Pavel, Pirrotta Vincenzo
Abstract excerpt
The genomic binding sites of Polycomb group (PcG) complexes have been found to cluster, forming Polycomb "bodies" or foci in mammalian or fly nuclei. These associations are thought to be driven by interactions between PcG complexes and result in enhanced repression. Here, we show that a Polycomb...
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