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Article

Down-regulation of miR-221 and miR-222 correlates with pronounced Kit expression in gastrointestinal stromal tumors.

International journal of oncology - 1 Feb 2011

Koelz Marita, Lense Josefine, Wrba Fritz, Scheffler Melanie, Dienes Hans Peter, Odenthal Margarete

Abstract excerpt

Gastrointestinal stromal tumors (GISTs), are characterized by mutations of the KIT or platelet-derived growth factor receptor-α gene and the constitutive expression of Kit, which is currently being studied as a potential therapeutic target. In this study, we addressed the question of whether the...

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Source

Identifiers

PMID: 21132270
DOI: 10.3892/ijo.2010.857

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21132270-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Down-regulation of miR-221 and miR-222 correlates with pronounced Kit expression in gastrointestinal stromal tumors.PMID 21132270Read ↗

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