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Article

MicroRNA-221 mediates the effects of PDGF-BB on migration, proliferation, and the epithelial-mesenchymal transition in pancreatic cancer cells.

PloS one - 1 Jan 2013

Su Anping, He Sirong, Tian Bole, Hu Weiming, Zhang Zhaoda

Abstract excerpt

The platelet-derived growth factor (PDGF) signaling pathway has been found to play important roles in the development and progression of human cancers by regulating the processes of cell proliferation, apoptosis, migration, invasion, metastasis, and the acquisition of the epithelial-mesenchymal transition (EMT) phenotype. Moreover, PDGF signaling has also been found to alter the expression profile of miRNAs,...

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Source

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Identifiers

PMID: 23967190
DOI: 10.1371/journal.pone.0071309
PMCID: PMC3742757

Genes

TRPS1

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