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Article

Upregulated miR-221/222 promotes cell proliferation and invasion and is associated with invasive features in retinoblastoma

22 May 2018

Abstract excerpt

BACKGROUND AND OBJECTIVES: MicroRNA (miR-221/222) is frequently overexpressed in many cancers and is associated with poor prognosis. However, the role of miR-221/222 in retinoblastoma (RB) remains unclear. This study aimed to detect the clinical significance of miR-221/222 in RB patients and explore its role in RB cells in vitro. METHODS: Expression of miR-221/222 was assessed in fresh RB tissue collected from 64...

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PMID: 29843209
DOI: 10.3233/cbm-170721

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