Article
miRNA profiling in gastrointestinal stromal tumors: implication as diagnostic and prognostic markers.
Epigenomics - 1 Jan 2015
Nannini Margherita, Ravegnini Gloria, Angelini Sabrina, Astolfi Annalisa, Biasco Guido, Pantaleo Maria A
Abstract excerpt
MicroRNAs are a class of short noncoding RNAs, that play a relevant role in multiple biological processes, such as differentiation, proliferation and apoptosis. Gastrointestinal stromal tumors (GIST) are considered as a paradigm of molecular biology in solid tumors worldwide, and after the discovery of specific alterations in the KIT and PDGFRA genes, they have emerged from anonymity to become a model for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.