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Article

MicroRNA-221 promotes colorectal cancer cell invasion and metastasis by targeting RECK.

FEBS letters - 3 Jan 2014

Qin Jun, Luo Meng

Abstract excerpt

MicroRNAs (miRNAs) have recently emerged as regulators of metastasis. We provide insight into the behavior of miR-221 in colorectal cancer (CRC) metastasis by showing that miR-221 is significantly upregulated in metastatic CRC cell lines and tissues. miR-221 overexpression enhances, whereas miR-221 depletion reduces CRC cell migration and invasion in vitro and metastasis in vivo. We identify RECK as a direct...

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PMID: 24269686
DOI: 10.1016/j.febslet.2013.11.014

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RECK

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MicroRNA-221 promotes colorectal cancer cell invasion and metastasis by targeting RECK.PMID 24269686Read ↗

miR-221 and miR-222 Simultaneously Target RECK and Regulate Growth and Invasion of Gastric Cancer CellsSemantic proximity Read ↗

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Increased miR‐222 in <i>H. pylori</i>‐associated gastric cancer correlated with tumor progression by promoting cancer cell proliferation and targeting RECKSemantic proximity Read ↗

MicroRNA-222 influences migration and invasion through MIA3 in colorectal cancerSemantic proximity Read ↗

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