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Article

RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication.

Biochemical and biophysical research communications - 7 Nov 2014

Wu Ming-Jhan, Ke Po-Yuan, Horng Jim-Tong

Abstract excerpt

Hepatitis C virus (HCV) is a positive-strand RNA virus responsible for chronic liver disease and hepatocellular carcinoma (HCC). RacGTPase-activating protein 1 (RacGAP1) plays an important role during GTP hydrolysis to GDP in Rac1 and CDC42 protein and has been demonstrated to be upregulated in s...

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Source

Identifiers

PMID: 25305482
DOI: 10.1016/j.bbrc.2014.10.008

Genes

CDC42

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25305482-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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