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Article

Dihydropyrimidinase‐like protein 3 expression is negatively regulated by <scp>MYCN</scp> and associated with clinical outcome in neuroblastoma

6 Sept 2013

Abstract excerpt

Dihydropyrimidinase-like proteins (DPYSLs) are a family of proteins developmentally regulated during maturation of the nervous system. Recently, members of the DPYSL family have been reported to be involved in cancer with low expression of DPYSL1 correlating with poor clinical outcomes in non-small cell lung cancer and functioning as a metastasis suppressor. Neuroblastoma (NB) is a tumor derived from precursor...

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PMID: 24011394
DOI: 10.1111/cas.12278

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