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Article

Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma.

Oncotarget - 27 Sept 2016

Eberhardt Allison, Hansen Jeanne N, Koster Jan, Lotta Louis T, Wang Simeng, Livingstone Emmett, Qian Kun, Valentijn Linda J, Zheng Yujun George, Schor Nina F, Li Xingguo

Abstract excerpt

Amplification or overexpression of MYCN is associated with poor prognosis of human neuroblastoma. We have recently defined a MYCN-dependent transcriptional signature, including protein arginine methyltransferase 1 (PRMT1), which identifies a subgroup of patients with high-risk disease. Here we provide several lines of evidence demonstrating PRMT1 as a novel regulator of MYCN and implicating PRMT1 as a potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proportional Hazards Models

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Source

Open in PubMed Open full text

Identifiers

PMID: 27571165
DOI: 10.18632/oncotarget.11556
PMCID: PMC5325390

Genes

MYCN
PRMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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