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Article

Differential role of CD133 and CXCR4 in renal cell carcinoma

15 Nov 2010

Abstract excerpt

The chemokine receptor CXCR4 and CD133, putative stem cell markers, were previously described in renal cancer (RCC). To evaluate the biological and prognostic role of CD133 and CXCR4 in RCC the expression was evaluated through qPCR and immunoblotting in human renal cancer cell lines (786-O, A498, ACHN, CAKI-1, SN12C, TK10, UO31) and patients biopsies. Renal cancer cells and surgical biopsies expressed functional...

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Identifiers

PMID: 21127401
DOI: 10.4161/cc.9.22.13680

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