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Article

MiRNA-1246 suppresses the proliferation and migration of renal cell carcinoma through targeting CXCR4.

1 Jun 2020

Abstract excerpt

OBJECTIVE: To uncover the role of miRNA-1246 in influencing the proliferative and migratory capacities of RCC by binding CXCR4 and downregulating its level. PATIENTS AND METHODS: Relative levels of miRNA-1246 and CXCR4 in 40 paired RCC tissues and adjacent normal tissues were determined. The binding relationship between miRNA-1246 and CXCR4 was confirmed by Dual-Luciferase reporter assay. Proliferative and...

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PMID: 32572911
DOI: 10.26355/eurrev_202006_21491

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