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Article

CD44 polymorphisms and its variants, as an inconsistent marker in cancer investigations.

Mutation research. Reviews in mutation research - 1 Jan 2000

Gomari Mohammad Mahmoudi, Farsimadan Marziye, Rostami Neda, Mahmoudi Zahra, Fadaie Mahmood, Farhani Ibrahim, Tarighi Parastoo

Abstract excerpt

Among cell surface markers, CD44 is considered the main marker for identifying and isolating the cancer stem cells (CSCs) among other cells and has attracted significant attention in a variety of research areas. Many studies have shown the essential roles of CD44 in initiation, metastasis, and tumorigenesis in different types of cancer; however, the validity of CD44 as a therapeutic or diagnostic target has not...

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PMID: 34083044
DOI: 10.1016/j.mrrev.2021.108374

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