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Article

CXCR4 is involved in CD133-induced EMT in non-small cell lung cancer.

International journal of oncology - 1 Feb 2017

Tu Zhenbo, Xie Songping, Xiong Meng, Liu Yinchu, Yang Xiangyong, Tembo Kingsley Miyanda, Huang Jie, Hu Weidong, Huang Xiaoxing, Pan Shan, Liu Pan, Altaf Ehtisham, Kang Ganjun, Xiong Jie, Zhang Qiuping

Abstract excerpt

Metastasis is the major cause of death in patients with non-small cell lung cancer (NSCLC), and epithelial-mesenchymal transition (EMT) has been observed to be one of the key regulators of metastasis in certain cancers as it confers an invasive phenotype. CD133 is a widely used cancer stem cell (CSC) marker, and CD133-positive cancer cells are thought to be tumor-initiating cells with CSC characteristics, while...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28000861
DOI: 10.3892/ijo.2016.3812

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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