Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CXCR4/CXCL12 expression and signalling in kidney cancer

1 Apr 2002

Abstract excerpt

CXCL12 (SDF-1), a CXC-chemokine, and its specific receptor, CXCR4, have recently been shown to be involved in tumourgenesis, proliferation and angiogenesis. Therefore, we analysed CXCL12alpha/CXCR4 expression and function in four human kidney cancer cell lines (A-498, CAKI-1, CAKI-2, HA-7), 10 freshly harvested human tumour samples and corresponding normal kidney tissue. While none of the analysed tumour cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokine receptors and signaling
Share to Immunotherapy and Immune Responses
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11953881
DOI: 10.1038/sj.bjc.6600221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CXCR4/CXCL12 expression and signalling in kidney cancerPMID 11953881Read ↗

Differential role of CD133 and CXCR4 in renal cell carcinomaSemantic proximity Read ↗

The Role of CXCL12 in Kidney Diseases: A Friend or Foe?Semantic proximity Read ↗

Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancerSemantic proximity Read ↗

Clinical Importance and Therapeutic Implications of the Pivotal CXCL12-CXCR4 (Chemokine Ligand-Receptor) Interaction in Cancer Cell MigrationSemantic proximity Read ↗

New insights on the role of CXCR4 in cancer metastasisSemantic proximity Read ↗

Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor GeneSemantic proximity Read ↗

CXCL12 and [N33A]CXCL12 in 5637 and HeLa cells: regulating HER1 phosphorylation via calmodulin/calcineurin.Semantic proximity Read ↗

CXCR2 agonists in ADPKD liver cyst fluids promote cell proliferation.Semantic proximity Read ↗

Cutting Edge: CXCR4-Lo: Molecular Cloning and Functional Expression of a Novel Human CXCR4 Splice VariantSemantic proximity Read ↗

[Clinical relevance of chemokine receptor CXCR4].Semantic proximity Read ↗

Expression of the Proto-Oncogene Axl in Renal Cell CarcinomaSemantic proximity Read ↗

CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.