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Article

A role for the DRD4 exon III VNTR in modifying the association between nicotine dependence and neuroticism.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Feb 2011

Ellis J A, Olsson C A, Moore E, Greenwood P, Van De Ven M O M, Patton G C

Abstract excerpt

INTRODUCTION: Neurotic psychopathology has been extensively examined as a risk factor for nicotine dependence (ND). Genetic stratification may partially explain variability in risk estimates. Genetic variants that compromise dopaminergic neurotransmission may motivate exposure to dopamine-stimulating agents, including nicotine. The 7-repeat allele of a Variable Number Tandem Repeat (VNTR) polymorphism in DRD4...

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Source

Identifiers

PMID: 21127031
DOI: 10.1093/ntr/ntq210

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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