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Article

Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Jun 2008

Laucht Manfred, Becker Katja, Frank Josef, Schmidt Martin H, Esser Günter, Treutlein Jens, Skowronek Markus H, Schumann Gunter

Abstract excerpt

OBJECTIVE: To clarify the nature of the association between dopamine genes and smoking by examining whether genetic variability in components of the dopamine pathway could explain refined phenotypes in adolescent smoking progression. METHOD: Data are from an ongoing prospective study of the long-term outcome of early risk factors studied since birth. At age 15 years, 220 participants (108 males, 112 females)...

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Source

Identifiers

PMID: 18434921
DOI: 10.1097/CHI.0b013e31816bff77

Genes

DRD2
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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